Pharmaceutical factory continuous elimination system
Continuous sterilization, that is , continuous sterilization of culture medium, also called continuous elimination. It is a way of sterilization. That is, the prepared and preheatedmedium(which can be feed or base material)is continuously pumped into a heating tower heated by direct steam, so that it can reach the sterilization temperature (126~132℃) in a short time. Then enter the maintenance tank (or maintenance tube), keep it at the sterilization temperature for a few minutes, and then enter the cooling tube, let it cool to the inoculation temperature and directly enter the pre-sterilized (empty tank sterilization)inside the fermentation tankThe process includes sterilization operations such as heating, maintenance and cooling. The cooling methods of the culture medium include spray cooling, vacuum cooling and plate heat exchanger.
The basic equipment for continuous sterilization generally includes:
①Ingredient preheating tank, heat exchange between the prepared liquid and the recovered waste heat is carried out to preheat to a certain temperature, which can reduce the steam consumption during sterilization;
②Ejector, the main function of the ejector is to make the high temperature steam and the material liquid contact and mix quickly, and make the temperature of the material liquid quickly rise to the sterilization temperature (126-132) ℃;
③ The heating time of the maintenance tank and the continuous elimination tower is very short. The sterilization during this period is not enough. The function of the maintenance tank is to keep the material liquid at the sterilization temperature for several minutes to achieve the purpose of sterilization;
④Cooling device, the feed liquid from the maintenance tank should be cooled by the cooling device, and after cooling to 40-50 ℃, it will be transported to the pre-sterilized fermentation tank for primary fermentation culture or as secondary and tertiary fermentation. Supplements are available.
The same star antibiotic base material and feeding continuous elimination system
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