Continuous sterilization is a sterilization method in which the medium is continuously heated outside the fermenter to maintain heat preservation and cooling through a special disinfection device, and then enters the fermenter. The main advantages of this method are saving a lot of steam and condensate water; High temperature, rapid sterilization, short heating time of materials, less destruction of nutrients; The sterilization time is short, the fermenter utilization rate is high; steam load equilibrium, high boiler utilization rate; It is suitable to use automatic control to reduce labor strength.